ChemoCentryx commences CCX140 Stage II trial in diabetic nephropathy ChemoCentryx.

ChemoCentryx commences CCX140 Stage II trial in diabetic nephropathy ChemoCentryx, Inc acné . Today announced the initiation of a Stage II clinical trial for CCX140, an orally-administered small molecule for the treatment of diabetic kidney disease . CCX140 functions by blocking the infiltration and activation of certain populations of monocyte and macrophages and various other cells bearing CCR2 that occurs during inflammation. As a precursor to the initiated scientific trials for CCX140 in sufferers with diabetic nephropathy lately, in an earlier Stage II scientific trial, ChemoCentryx assessed the safety, tolerability and clinical effects of CCX140 in type 2 diabetics with regular kidney function.

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