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Furthermore, we screened numerous tumours from individual biopsies – sarcomas, melanomas along with prostate, colon, breast, mind and lung cancers – and verified EphA3 expression on stromal cells and newly forming blood vessels, Professor Scott stated. Our research results indicate that the tumour micro-environment is essential, and monoclonal antibodies against EphA3 are one way to focus on and kill a variety of solid tumours along with blood cancers. Currently, KaloBios Pharmaceuticals is testing the anti-EphA3 antibody KB004 in a multi-centre Stage I/II scientific trial in Melbourne and the US in individuals with EphA3 expressing blood malignancies: AML, Myelofibrosis and MDS.