5 cups of grapes a day for a person. ‘The portions are fair,’ said Shay, ‘making our results more applicable to the human diet plan.’ Over a 10-week trial, the high-fat-fed mice developed fatty liver and diabetic symptoms – ‘the same metabolic effects we see in lots of over weight, sedentary people,’ Shay stated. However the chubby mice that got the extracts accumulated less fat within their livers, plus they had lower blood sugar, than the ones that consumed the high-unwanted fat diet by itself. Ellagic acid proved to be a powerhouse in this experiment, too, lowering the high-fat-fed mice’s blood sugar to nearly the levels of the lean, normally fed mice.‘This new test addresses a sixty-year-old issue,’ said Dimitri Monos, Ph.D., director of the Immunogenetics Laboratory in the Division of Genomic Diagnostics at The Kids's Medical center of Philadelphia. ‘Since the discovery of HLAs in the early 1950s, it’s been a challenge to accurately and thoroughly characterize HLA gene sequences. We now have used next-generation sequencing tools to significantly advance HLA typing. ‘ CHOP may be the first hospital to offer this new extensive HLA-typing test anywhere, based on extensive study by Monos and colleagues. ‘This is a new, disruptive technology, with the potential to transform analysis and medical practice, in transplantation and additional fields,’ stated Robert Doms, M.D., Ph.D., pathologist-in-chief at CHOP.