In 2000, there were 11,800 drink – drive accidents in Great Britain, which in 530 deaths. It is estimated that a total of 5,543 alcohol-related deaths in England and Wales in 2000. In 1995:.
Notes:In 1992 , the government introduced the weekly guideline that men drink less than 21 units per week and women under 14 units per week. In 1995, the guidelines were on day of a week, advice that men should not be more than 4 units per day and no more than 3 no more than 3 units per day changed. One unit is 8 grams of alcohol as equivalent to a half pint of ordinary strength beer, a small glass of wine or a measure of spirits is defined. The GHS figures before 1998 /99 are will be weighted and unweighted from 1998/99 from. Here.Simon, Richard, ‘Optimal Two-Stage Designs of the phase II trials, ‘Controlled Clinical Trials 10:1-10 .
Nektar Therapeutics Towith Nektar Therapeutics announced an advanced Stage 2 construction plan on NKTR-102 . National’s new in colon cancer patients with KRAS mutant gene status at its Phase 2 study for advanced colon cancer. Platin -refractory ovarian and advanced breast refractory to refractory to anthracycline and / or The taxane – based therapy: In addition, NKTR-102 be evaluated in Phase 2 trials to two new indications. Those studies in the second in the second half of 2008.